陈翊平

            教授

个人简介

       2023年9月-至今，大连工业大学，教授/博导

       2018年8月-2023年8月，华中农业大学食品科学技术学院，教授/博导

       2016年4月-2018年7月，国家纳米科学中心/中科院纳米生物效应与安全性重点实验室，副研究员

       2013年7月-2016年3月，国家纳米科学中心/中科院纳米生物效应与安全性重点实验室，助理研究员

       2010年9月-2013年7月，北京师范大学，分析化学，理学博士

       2007年9月-2010年7月，华中农业大学，食品营养与安全，工学硕士

       2003年9月-2007年7月，华中农业大学，环境科学，理学学士

社会兼职

     Frontiers in Bioengineering and Biotechnology副主编（中科院二区）

研究方向

       1. 食品安全快速检测理论及方法

       2. 食品安全高效控制理论及技术

主要成果

         入选国家青年拔尖人才计划、北京市科技新星和中国科学院青年创新促进会。以第一完成人分别获得了湖北省技术发明二等奖、大北农科技创新奖和中国分析测试协会科学技术二等奖。主持5项国家级科研项目，3项国家自然科学基金和2项科技部课题。近5年以第一或通讯作者在Angewandte Chemie International Edition, ACS Nano, Analytical Chemistry，Journal of Agricultural and Food Chemistry, Food Chemistry等刊物发表中科院1区Top论文65篇（其中IF>10论文20篇）。授权17项国家发明专利（第1发明人），其中8项发明专利实现了550万元成果转化。

科研项目

       1. 2022-2026，国家重点研发项目“动物源性产品中有害物耐低温实时磁电传感检测技术及装置研发”，项目号：2022YFF0607902（主持）

       2. 2023-2025   国家青年拔尖人才项目 食品安全快速检测新理论及方法 （主持）

       3. 2022-2025，面上项目“食源性沙门氏菌检测的顺磁离子-纳米磁探针信号协同增强传感机制研究”，项目号：32172293（主持）

       4. 2022-2024，湖北省重点研发项目“淡水水产品危害物高通量快检装备研发”，项目号：2022BBA0057（主持）

       5. 2021-2023，小孔电阻颗粒计数免疫传感设备的成果转化（主持）

       6. 2020-2022，科技部“十三五”食品安全重点研发计划子课题“粮食油料类口岸食品模块化快检组合产品的集成研发”项目号：2019YCF1605502-3（主持）

       7. 2017-2020，面上基金“基于click反应的磁弛豫时间免疫传感器在诊断细菌感染中的研究”，项目号：81671784（主持）

       8. 2016-2018，青年基金“基于多功能磁探针和生物发光信号放大系统的免疫分析方法研究”，项目号：21505027（主持）

       9. 2019-2021，武汉市科技局应用前沿项目“基于固相微萃取的低场核磁免疫传感器在果蔬农药残留快速高灵敏检测中的研究”，项目号：2019020701011426（主持）

       10. 2021-2023，岭南实验室开放课题“基于噬菌体识别的微通道电阻生物传感器检测食源性单增李斯特菌的研究”，项目号：NZ2021036（主持）

出版著作和论文

       代表论文：

       1) Weiqi Zhao#, Yang Zhou#, Yao-Ze Feng, Xiaohu Niu, Yongkun Zhao, Junpeng Zhao, Yongzhen Dong, Mingqian Tan, Yunlei Xianyu*, and Yiping Chen*. Computer Vision-Based Artificial Intelligence-Mediated Encoding-Decoding for Multiplexed Microfluidic Digital Immunoassay. ACS Nano, 2023, 17 (14), 13700-13714. (中科院一区, IF=17.1)

       2) Peng Lu, Chen Zhan, Chenxi Huang, Lin Miao, Rui Chen, Yongkun Zhao, Yunlei Xianyu* Xiaohua Chen*, Yiping Chen*. A Wash-Free Spheres-on-Sphere Strategy for On-Site and Multiplexed Biosensing. ACS Nano., 2024, DOI: 10.1021/acsnano.3c12289 (中科院一区, IF=17.1)

       3) Luyu Wei Zhilong Wang, Hetong Zhang, Feng Jiang, Yiping Chen*. Recent advances in magnetic relaxation switching biosensors for animal-derived food safety detection. Trends Food Sci Tech., 2024, 146, 104387. (中科院一区, IF=15.3)

       4) Junping Wen, Minjie Han, Niu Feng, Guoxun Chen, Feng Jiang, Jianhan Lin, Yiping Chen*. A digital platform for One-Pot signal enhanced foodborne pathogen detection based on mesophilic argonaute-driven polydisperse microdroplet reactors and machine learning. Chem. Eng. J., 2024, 482, 148845. (中科院一区, IF=15.1)

       5) Letian Li, Mengjiao Wang, Junping Wen, Feng Hong, Liangqiong Ren, Feng Jiang, Yiping Chen*. Clostridium butyricum Argonaute-powered programmable platform using a magnetic nanoparticle tetrahedral DNA encoding system for the ultrasensitive and multiplexed detection of non-nucleic acid targets. Chem. Eng. J., 2024, 484, 149548. (中科院一区, IF=15.1)

       6) Feng Hong, Liangqiong Ren, Yiping Chen*. Kill Three Birds with One Stone: Zr-MOF-Mediated Composite Multi-Functional Materials to Enhance The Efficiency For Fluorescent And Colorimetric Dual-Signal Readout Bioassay. Chem. Eng. J., 2023, 452, 139149. (中科院一区, IF=15.1)

       7) Lei Bi, Yiping Chen*, Chen Wang, Jing Su, Gang Pan*; Microalgae-derived Cellulise/inorganic Nanocomposite Rattle-Type Microspheres as an Advanced Sensor for Pollutant Detection, Chem. Eng. J., 2020, 395, 125073. (中科院一区, IF=15.1)
       8) Letian Li#, Feng Hong#, Shixing Pan, Liangqiong Ren, Ruiheng Xiao, Puyue Liu, Nan Li, Jianlong Wang, Yiping Chen*. "Lollipop" particle counting immunoassay based on antigen-powered CRISPR-Cas12a dual signal amplification for the sensitive detection of deoxynivalenol in the environment and food samples. J. Hazard. Mater., 2023,455, 131573. (中科院一区, IF=13.6)

       9) Yongzhen Dong#, Cong-ying Wen#, Yongxin She, Yu Zhang, Yiping Chen*, and Jingbin Zeng*. Magnetic Relaxation Switching Immunoassay Based on Hydrogen Peroxide-Mediated Assembly of Ag@Au–Fe3O4 Nanoprobe for Detection of Aflatoxin B1. Small, 2021, 2104596. (中科院一区, IF=13.3)

       10) Junping Wen, Liangqiong Ren, Qifu He, Junwang Bao, Xiuwen Zhang, Zhixiong Pi, Yiping Chen*. Contamination-free V-shaped ultrafast reaction cascade transferase signal amplification driven CRISPR/Cas12a magnetic relaxation switching biosensor for bacteria detection. Biosens. Bioelectron. 2023, 219, 114790. (中科院一区, IF=12.6)

       11) Peng Lu#, Chen Zhan#, Chenxi Huang, Yang Zhou, Feng Hong, Zhilong Wang, Yongzhen Dong, Nan Li, Qifu He, and Yiping Chen*. Cartridge voltage-sensitive micropump immunosensor based on a self-assembled polydopamine coating mediated signal amplification strategy. Biosens. Bioelectron., 2023, 226, 115087. (中科院一区, IF=12.6)

       12) Luyu Wei, Zhilong Wang, Long Wu, Yiping Chen*. CRISPR/Cas12a-based magnetic relaxation switching biosensor for nucleic acid amplification-free and ultrasensitive detection of methicillin-resistant Staphylococcus aureus. Biosens. Bioelectron., 2023, 222, 114984. (中科院一区, IF=12.6)

       13) Liangqiong Ren, Feng Hong, and Yiping Chen*. Enzyme-free catalytic hairpin assembly reaction-mediated micro-orifice resistance assay for the ultrasensitive and low-cost detection of Listeria monocytogenes. Biosens. Bioelectron. 2022, 214, 114490. (中科院一区, IF=12.6)

       14) Yongzhen Dong#, Rui Chen#, Long Wu, Xiaohong Wang, Feng Jiang, Zhiyong Fan, Chenxi Huang, and Yiping Chen*. Magnetic relaxation switching biosensor via polydopamine nanoparticle mediated click chemistry for detection of chlorpyrifos. Biosens. Bioelectron. 2022, 207114127. (中科院一区, IF=12.6)

       15) Yunlei Xianyu#, Yongzhen Dong#, Zhuo Zhang, Zhanhui Wang, Wenbo Yu, Zhilong Wang, Yiping Chen*; Gd3+-nanoparticle-enhanced multivalent biosensing that combines magnetic relaxation switching and magnetic separation, Biosens. Bioelectron, 2020, 155, 112106. (中科院一区, IF=12.6)

       16) Zhilong Wang, Luyu Wei, Shilong Ruan, Yiping Chen*. CRISPR/Cas12a-Assisted Chemiluminescence Sensor for Aflatoxin B1 Detection in Cereal Based on Functional Nucleic Acid and In-Pipet Rolling Circle Amplification. J. Agric. Food Chem., 2023, 71, 10, 4417-4425. (中科院一区, IF=6.1)

       17) Weiqi Zhao, Chenxi Huang, Binjie Zhao, Junping Wen, Yingying Lu, Nan Li, Qifu He, Junwang Bao, Xiuwen Zhang, Zhixiong Pi, Yongzhen Dong, and Yiping Chen*. Magnetic relaxation switching immunosensors via a click chemistry-mediated controllable aggregation strategy for direct detection of Chlorpyrifos. J. Agric. Food Chem., 2023, 71, 3, 1727-1734. (中科院一区, IF=6.1)

       18) Luyu Wei, Zhilong Wang, Yiping Chen*. Optical Biosensor for Ochratoxin A Detection in Grains Using an Enzyme-Mediated Click Reaction and Polystyrene Nanoparticles. J. Agric. Food Chem. 2022, 70, 46, 14798-14804. (中科院一区, IF=6.1)

       19) Yongzhen Dong#, Wenshu Zheng#, Da Chen, Xiujuan Li, Jia Wang, Zhilong Wang, and Yiping Chen*. Click Reaction-Mediated T2 Immunosensor for Ultrasensitive Detection of Pesticide Residues via Brush-like Nanostructure Triggered Coordination Chemistry. J. Agric. Food Chem. 2019, 67, 9942-9949. (中科院一区, IF=6.1)

       20) Wei Huang, Luyu Wei, Rongbin Nie, Xiaohan Li, Peng Lu, Yiping Chen*. Rapid and quantitative determination of Deoxynivalenol in cereal through the combination of magnetic solid-phase extraction and optical fiber-based homogeneous chemiluminescence immunosensor. Food Chem., 2023, 410, 135356. (中科院一区, IF=8.8)

       21) Chenxi Huang, Junpeng Zhao, Rongsheng Lu, Jia Wang, Sam R. Nugen, Yiping Chen*, Xiaohong Wang*. A phage-based magnetic relaxation switching biosensor using bioorthogonal reaction signal amplification for Salmonella detection in foods. Food Chem., 2023, 400, 134035. (中科院一区, IF=8.8)

       22) Luyu Wei, Fu Jiao, Zhilong Wang, Long Wu, Daming Dong*, and Yiping Chen*. Enzyme-modulated photothermal immunoassay of chloramphenicol residues in milk and egg using a self-calibrated thermal imager. Food Chem., 2022, 392, 133232. (中科院一区, IF=8.8)

       23) Liangqiong Ren, Wanxian Feng, Feng Hong, Zhilong Wang, Hanying Huang, and Yiping Chen*. One-step homogeneous micro-orifice resistance immunoassay for detection of chlorpyrifos in orange samples. Food Chem., 2022, 132712, 386. (中科院一区, IF=8.8)

       24) Xiaobao Qi, Zhilong Wang, Rongsheng Lu, Jiawei Liu, Yue Li, and Yiping Chen*. One-step and DNA amplification-free detection of Listeria monocytogenes in ham samples: Combining magnetic relaxation switching and DNA hybridization reaction. Food Chem., 2021, 338, 127837. (中科院一区, IF=8.8)

       25) Yang Zhou, Weiqi Zhao, Yaoze Feng, Xiaohu Niu, Yongzhen Dong, and Yiping Chen*. Artificial intelligence-assisted digital immunoassay based on a programmable-particle-decoding technique for multitarget ultrasensitive detection. Anal. Chem., 2023, 95, 2, 1589-1598. (中科院一区, IF=7.4)

       26) Niu Feng, Xuewen Peng, Zhipan Wang, Xiaoping Yu, Xuping Shentu, Yiping Chen*. Label-Free Microchannel Immunosensor Based on Antibody-Antigen Biorecognition-Induced Charge Quenching. Anal. Chem. 2022, 94, 48, 16778-16786. (中科院一区, IF=7.4)

       27) Zhilong Wang, Luyu Wei, Lingwen Zeng, Niu Feng, Jianjun Chen, and Yiping Chen*. Click Chemistry-Mediated Particle Counting Sensing via Cu(II)-Polyglutamic Acid Coordination Chemistry and Enzymatic Reaction. Anal. Chem. 2022, 94, 13, 5293-5300. (中科院一区, IF=7.4)

       28) Huiyu He, Rongbin Nie, Peng Lu, Xuewen Peng, Xiaohan Li, and Yiping Chen*. Low-Cost and Convenient Microchannel Resistance Biosensing Platform by Directly Translating Biorecognition into a Current Signal. Anal. Chem. 2021, 93, 45, 15049-15057. (中科院一区, IF=7.4)

       29) Zhilong Wang, Jiawei Liu, Yanlian Yang, Ping Li, Kaikai Li, Yunlei Xianyu*, Yiping Chen*, and Bin Li. Versatile Biosensing Toolkit Using an Electronic Particle Counter. Anal. Chem. 2021, 93, 15, 6178-6187. (中科院一区, IF=7.4)

       30) Wenshu Zheng#; Lingwen Zeng#; Yiping Chen*; Bioorthogonal reactions amplify magnetic nanoparticles binding and assembly for ultrasensitive magnetic resonance sensing, Anal. Chem., 2020, 92, 2787-2793. (中科院一区, IF=7.4)

在读学生人数

        在读博士研究生12名，硕士研究生18名。

毕业学生人数

        已毕业博士研究生2名，硕士研究生13名。